Technology Discussion—SNPs (“Snips”), Business and Industry Trends Analysis

The holy grail of genomics is the search for single nucleotide polymorphisms (SNPs).  These are DNA sequence variations that occur when a single nucleotide (A, T, C or G) in the genome sequence is altered.  For example an SNP might change the DNA sequence AAGGCTAA to ATGGCTAA.  SNPs occur in every 100 to 1,000 bases along the 3 billion-base human genome.  SNPs can occur in both coding (gene) and noncoding regions of the genome.  Many SNPs have no effect on cell function, but scientists believe others could predispose people to diseases or influence their response to a drug. Variations in…

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